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Thabele M. Leslie-Mazwi, M.D.

Dr. Thabele Leslie-Mazwi

Titles and Contact Information

Attending Neurologist, Massachusetts General Hospital Stroke Service, Neurocriticial Care, Neuroendovascular Service

Instructor, Harvard Medical School

Appointments: 617.726.1067
Fax Number: 617.726.3089

Affiliations and Profiles

Clinical Interests

  • Neurocritical care

Clinical Background

1996 - 2000 Medical School University of Zimbabwe
2004 - 2008 Residency Mayo Clinic
2008 - 2010 Fellowship Massachusetts General Hospital/Brigham and Women's Hospital
Neurologic Critical Care


Thanabalasundaram G, Hernández-Durán S, Leslie-Mazwi T, Ogilvy CS
Cortical non-aneurysmal subarachnoid hemorrhage post-carotid endarterectomy: a case report and literature review.
Springerplus. 2013 ; 2 (): 571

Liggins JT, Yoo AJ, Mishra NK, Wheeler HM, Straka M, Leslie-Mazwi TM, Chaudhry ZA, Kemp S, Mlynash M, Bammer R, Albers GW, Lansberg MG,
A score based on age and DWI volume predicts poor outcome following endovascular treatment for acute ischemic stroke.
Int J Stroke. 2013 Nov 10; ():

Leslie-Mazwi TM, Chandra RV, Simonsen CZ, Yoo AJ
Elderly patients and intra-arterial stroke therapy.
Expert Rev Cardiovasc Ther. 2013 Dec ; 11 (12): 1713-23

Zaidat OO, Castonguay AC, Gupta R, Sun CH, Martin C, Holloway WE, Mueller-Kronast N, English JD, Linfante I, Dabus G, Malisch TW, Marden FA, Bozorgchami H, Xavier A, Rai AT, Froehler MT, Badruddin A, Nguyen TN, Taqi MA, Abraham MG, Janardhan V, Shaltoni H, Novakovic R, Yoo AJ, Abou-Chebl A, Chen PR, Britz GW, Kaushal R, Nanda A, Issa MA, Nogueira RG
North American Solitaire Stent Retriever Acute Stroke registry: post-marketing revascularization and clinical outcome results.
J Neurointerv Surg. 2013 Sep 23; ():

Walcott BP, Berkhemer OA, Leslie-Mazwi TM, Chandra RV, Ogilvy CS, Yoo AJ
Multimodal endovascular treatment of a vertebrovertebral fistula presenting with subarachnoid hemorrhage and hydrocephalus.
J Clin Neurosci. 2013 Sep ; 20 (9): 1295-8

Leslie-Mazwi TM, Heddier M, Nordmeyer H, Stauder M, Velasco A, Mosimann PJ, Chapot R
Stent retriever use for retrieval of displaced microcoils: a consecutive case series.
AJNR Am J Neuroradiol. 2013 Oct ; 34 (10): 1996-9

Leslie-Mazwi TM
Antiplatelet testing in neurointervention: we cannot ignore the signs.
J Neurointerv Surg. 2013 Jul ; 5 (4): 277-9

Morais LT, Leslie-Mazwi TM, Lev MH, Albers GW, Yoo AJ
Imaging-based selection for intra-arterial stroke therapies.
J Neurointerv Surg. 2013 May ; 5 Suppl 1 (): i13-20

Yoo AJ, Leslie-Mazwi TM, Jovin TG
Future directions in IAT: better studies, better selection, better timing and better techniques.
J Neurointerv Surg. 2013 May ; 5 Suppl 1 (): i1-6

Kidwell CS, Jahan R, Gornbein J, Alger JR, Nenov V, Ajani Z, Feng L, Meyer BC, Olson S, Schwamm LH, Yoo AJ, Marshall RS, Meyers PM, Yavagal DR, Wintermark M, Guzy J, Starkman S, Saver JL,
A trial of imaging selection and endovascular treatment for ischemic stroke.
N Engl J Med. 2013 Mar 7; 368 (10): 914-23

Hirsch JA, Donovan WD, Leslie-Mazwi TM, Nicola GN, Manchikanti L, Silva E
Component coding and the neurointerventionalist: a tale with an end.
J Neurointerv Surg. 2013 Nov ; 5 (6): 615-9

Mehta B, Leslie-Mazwi TM, Chandra RV, Chaudhry ZA, Rabinov JD, Hirsch JA, Schwamm LH, Rost NS, Yoo AJ
Assessing variability in neurointerventional practice patterns for acute ischemic stroke.
J Neurointerv Surg. 2013 May ; 5 Suppl 1 (): i52-7

Hirsch JA, Mehta BP, Chandra RV, Leslie-Mazwi TM, Rost NS, Yoo AJ
Efficacy of intra-arterial therapy in the elderly requires further study.
J Neurointerv Surg. 2012 Sep 19; ():

Yoo AJ, Chandra RV, Leslie-Mazwi TM
Catching strokes before they happen: the importance of early neuroimaging findings in TIA and minor ischemic stroke.
Expert Rev Cardiovasc Ther. 2012 Jul ; 10 (7): 847-50

Chandra RV, Leslie-Mazwi TM, Oh DC, Chaudhry ZA, Mehta BP, Rost NS, Rabinov JD, Hirsch JA, González RG, Schwamm LH, Yoo AJ
Elderly patients are at higher risk for poor outcomes after intra-arterial therapy.
Stroke. 2012 Sep ; 43 (9): 2356-61

Leslie-Mazwi TM, Chandra RV, Yoo AJ, Rabinov JD, Hirsch JA
Hemorrhagic complications with prasugrel therapy for vascular neurointerventional procedures.
J Neurointerv Surg. 2013 Jul ; 5 (4): 344-5

Yoo AJ, Leslie-Mazwi TM, Riedel CH, Chandra RV
Pathologic validation of clot length determined using thin section non-contrast CT.
J Neurointerv Surg. 2013 Jul ; 5 (4): e16

Yoo AJ, Chaudhry ZA, Leslie-Mazwi TM, Chandra RV, Hirsch JA, González RG, Simonsen CZ
Endovascular treatment of acute ischemic stroke: current indications.
Tech Vasc Interv Radiol. 2012 Mar ; 15 (1): 33-40

Hirsch JA, Chandra RV, Leslie-Mazwi TM
Pipeline, aneurysms and the FDA.
J Neurointerv Surg. 2012 Jul ; 4 (4): 314; author reply 314

Gupta AC, Schaefer PW, Chaudhry ZA, Leslie-Mazwi TM, Chandra RV, González RG, Hirsch JA, Yoo AJ
Interobserver reliability of baseline noncontrast CT Alberta Stroke Program Early CT Score for intra-arterial stroke treatment selection.
AJNR Am J Neuroradiol. 2012 Jun ; 33 (6): 1046-9

Leslie-Mazwi TM, Sims JR, Hirsch JA, Nogueira RG
Periprocedural blood pressure management in neurointerventional surgery.
J Neurointerv Surg. 2011 Mar ; 3 (1): 66-73

Leslie-Mazwi TM, Chandra RV, Oh DC, Nogueira RG
Novel use of prasugrel for intracranial stent thrombosis.
J Neurointerv Surg. 2011 Dec 1; 3 (4): 358-60

Chandra RV, Leslie-Mazwi TM, Oh D, Mehta B, Yoo AJ
Extracranial internal carotid artery stenosis as a cause of cortical subarachnoid hemorrhage.
AJNR Am J Neuroradiol. 2011 Mar ; 32 (3): E51-2; author reply E53

Leslie-Mazwi TM, Avery LL, Sims JR
Intra-arterial air thrombogenesis after cerebral air embolism complicating lower extremity sclerotherapy.
Neurocrit Care. 2009 ; 11 (2): 247-50

Leslie-Mazwi TM, Avery LL, Sims JR
Intra-arterial air thrombogenesis after cerebral air embolism complicating lower extremity sclerotherapy.
Neurocrit Care. 2009 ; 11 (1): 97-100

Leslie-Mazwi TM, Brott TG, Brown RD, Worrall BB, Silliman SL, Case LD, Frankel MR, Rich SS, Meschia JF
Sex differences in stroke evaluations in the Ischemic Stroke Genetics Study.
J Stroke Cerebrovasc Dis. ; 16 (5): 187-93

Leslie-Mazwi T, Deen HG
Repeated fracture of a vertebral body after treatment with balloon kyphoplasty: case illustration.
J Neurosurg Spine. 2006 Mar ; 4 (3): 270

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In the News

The MGH Neurology Department placed 4th in US News Neurology / NeuroSurgery rankings for 2013-14.

Educational Video

Still from the Stroke Evaluation simulation

This video simulation of an Emergency stroke evaluation illustrates the care of patients with acute stroke by the MGH Acute Stroke team.