Titles and Contact Information
Associate Neurologist, Massachusetts General Hospital
Associate Neurologist, Brigham and Women's Hospital
Consulting Staff in Neurology, Spaulding Rehabilitation Hospital
Investigator, Rehabilitation R&D, Dept. Veterans Affairs
Visiting Associate Professor of Neurology, Harvard Medical School
Associate Professor of Engineering, Brown University
Appointments: (617) 726-4218
Affiliations and Profiles
Clinical Interests
- Stroke
- Neurocritical Care
Current Projects
BrainGate Clinical Trials
Clinical Background
| 1999 |
M.D. Degree
|
Emory University School of Medicine |
| 1999 |
Ph.D. Degree
|
Emory University Neuroscience |
| 2000 |
Internship
|
Grady Memorial Hospital and Emory Affiliated Hospitals
Internal Medicine |
| 2000 - 2003 |
Residency
|
Massachusetts General Hospital / Brigham and Women's Hospital
Neurology |
| 2003 - 2004 |
Fellowship
|
Massachusetts General Hospital / Brigham and Women's Hospital
Stroke and NeuroCritical Care |
| 2005 |
Board Certification
|
Neurology |
| 2008 |
Board Certification
|
Vascular Neurology |
| 2011 |
Board Certification
|
Neurocritical Care |
Articles
Chadwick
EK, Blana
D, Simeral
JD, Lambrecht
J, Kim
SP, Cornwell
AS, Taylor
DM, Hochberg
LR, Donoghue
JP, Kirsch
RF
Continuous neuronal ensemble control of simulated arm reaching by a human with tetraplegia.
J Neural Eng.
2011
Jun
;
8
(3):
034003
Truccolo
W, Donoghue
JA, Hochberg
LR, Eskandar
EN, Madsen
JR, Anderson
WS, Brown
EN, Halgren
E, Cash
SS
Single-neuron dynamics in human focal epilepsy.
Nat Neurosci.
2011
May
;
14
(5):
635-41
Simeral
JD, Kim
SP, Black
MJ, Donoghue
JP, Hochberg
LR
Neural control of cursor trajectory and click by a human with tetraplegia 1000 days after implant of an intracortical microelectrode array.
J Neural Eng.
2011
Apr
;
8
(2):
025027
Kim
SP, Simeral
JD, Hochberg
LR, Donoghue
JP, Friehs
GM, Black
MJ
Point-and-click cursor control with an intracortical neural interface system by humans with tetraplegia.
IEEE Trans Neural Syst Rehabil Eng.
2011
Apr
;
19
(2):
193-203
Ajiboye
AB, Hochberg
LR, Donoghue
JP, Kirsch
RF
Application of system identification methods for decoding imagined single-joint movements in an individual with high tetraplegia.
Conf Proc IEEE Eng Med Biol Soc.
2010
;
2010
():
2678-81
Malik
WQ, Truccolo
W, Brown
EN, Hochberg
LR
Efficient decoding with steady-state Kalman filter in neural interface systems.
IEEE Trans Neural Syst Rehabil Eng.
2011
Feb
;
19
(1):
25-34
Keller
CJ, Truccolo
W, Gale
JT, Eskandar
E, Thesen
T, Carlson
C, Devinsky
O, Kuzniecky
R, Doyle
WK, Madsen
JR, Schomer
DL, Mehta
AD, Brown
EN, Hochberg
LR, Ulbert
I, Halgren
E, Cash
SS
Heterogeneous neuronal firing patterns during interictal epileptiform discharges in the human cortex.
Brain.
2010
Jun
;
133
(Pt 6):
1668-81
Nurmikko
AV, Donoghue
JP, Hochberg
LR, Patterson
WR, Song
YK, Bull
CW, Borton
DA, Laiwalla
F, Park
S, Ming
Y, Aceros
J
Listening to Brain Microcircuits for Interfacing With External World-Progress in Wireless Implantable Microelectronic Neuroengineering Devices: Experimental systems are described for electrical recording in the brain using multiple microelectrodes and short range implantable or wearable broadcasting units.
Proc IEEE Inst Electr Electron Eng.
2010
;
98
(3):
375-388
Truccolo
W, Hochberg
LR, Donoghue
JP
Collective dynamics in human and monkey sensorimotor cortex: predicting single neuron spikes.
Nat Neurosci.
2010
Jan
;
13
(1):
105-11
Kim
SP, Simeral
JD, Hochberg
LR, Donoghue
JP, Black
MJ
Neural control of computer cursor velocity by decoding motor cortical spiking activity in humans with tetraplegia.
J Neural Eng.
2008
Dec
;
5
(4):
455-76
Hochberg
LR
Turning thought into action.
N Engl J Med.
2008
Sep
11;
359
(11):
1175-7
Truccolo
W, Friehs
GM, Donoghue
JP, Hochberg
LR
Primary motor cortex tuning to intended movement kinematics in humans with tetraplegia.
J Neurosci.
2008
Jan
30;
28
(5):
1163-78
Kim
SP, Simeral
JD, Hochberg
LR, Donoghue
JP, Friehs
GM, Black
MJ
Multi-state decoding of point-and-click control signals from motor cortical activity in a human with tetraplegia.
3rd International IEEE-EMBS Conference 2007 May:486-489.
;
():
Donoghue
JP, Hochberg
LR, Nurmikko
AV, Black
MJ, Simeral
JD, Friehs
G
Neuromotor prosthesis development.
Med Health R I.
2007
Jan
;
90
(1):
12-5
Hochberg
LR, Taylor
DM
Intuitive prosthetic limb control.
Lancet.
2007
Feb
3;
369
(9559):
345-6
Donoghue
JP, Nurmikko
A, Black
M, Hochberg
LR
Assistive technology and robotic control using motor cortex ensemble-based neural interface systems in humans with tetraplegia.
J Physiol.
2007
Mar
15;
579
(Pt 3):
603-11
Hochberg
LR, Donoghue
JP
Sensors for brain-computer interfaces.
IEEE Eng Med Biol Mag.
;
25
(5):
32-8
Aaron
RK, Herr
HM, Ciombor
DM, Hochberg
LR, Donoghue
JP, Briant
CL, Morgan
JR, Ehrlich
MG
Horizons in prosthesis development for the restoration of limb function.
J Am Acad Orthop Surg.
2006
Oct
;
14
(10 Suppl):
S198-204
Hochberg
LR, Serruya
MD, Friehs
GM, Mukand
JA, Saleh
M, Caplan
AH, Branner
A, Chen
D, Penn
RD, Donoghue
JP
Neuronal ensemble control of prosthetic devices by a human with tetraplegia.
Nature.
2006
Jul
13;
442
(7099):
164-71
Kübler
A, Mushahwar
VK, Hochberg
LR, Donoghue
JP
BCI Meeting 2005--workshop on clinical issues and applications.
IEEE Trans Neural Syst Rehabil Eng.
2006
Jun
;
14
(2):
131-4
Hochberg
LR, Sims
JR, Davis
BT
West Nile encephalitis in Massachusetts.
N Engl J Med.
2002
Mar
28;
346
(13):
1030-1
Burrow
M, Dugger
J, Humphrey
DR, Reed
DJ, Hochberg
LR
Cortical control of a robot using a time-delay neural network.
International Conference on Rehabilitation Robotics, 1997.
;
():