Titles and Contact Information
Director, Stroke Service, Massachusetts General Hospital
Assistant in Neurology
Director, Stroke Prevention Clinic, Massachusetts General Hospital
Appointments: 617.726.8459
Fax Number: 617.643.3939
Affiliations and Profiles
Clinical Interests
- Stroke
- TIAS
- Cerebrovascular Disorders
- Neurosonology
Clinical Background
1990 |
M.D. Degree
|
Brown University School of Medicine |
1994 |
Residency
|
Rhode Island Hospital Neurology |
1995 |
Fellowship
|
Brown University Cerebrovascular Disease |
1996 |
|
Harvard School of Public Health Masters in Public Health |
Articles
Stein
J, Shafqat
S, Doherty
D, Frates
EP, Furie
KL
Family member knowledge and expectations for functional recovery after stroke.
Am J Phys Med Rehabil 2003; 82: 169-74..
;
():
Kelly
PJ, Furie
KL, Kistler
JP, Barron
M, Picard
EH, Mandell
R, Shih
VE
Stroke in young patients with hyperhomocysteinemia due to cystathionine beta synthase deficiency.
Neurology 2003; 60: 275-9..
;
():
Kelly
PJ, Shih
VE, Kistler
JP, Barron
M, Lee
H, Mandell
R, Furie
KL
Low vitamin B6 but not homocysteine is associated with increased risk of stroke and transient ischemic attack in the era of folic acid grain supplementation.
Stroke 2003; 34:e51-4..
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():
Stein
J, Shafqat
S, Doherty
D, Frates
EP, Furie
KL
Patient knowledge and expectations for functional recovery after stroke.
Am J Phys Med Rehabil. 2003; 82: 591-6..
;
():
Kelly
PJ, Furie
KL, Shafqat
S, Rallis
N, Chang
Y, Stein
J
Functional recovery following rehabilitation after hemorrhagic and ischemic stroke.
Arch PM&R 2003; 84: 968-72..
;
():
Kelly
PJ, Stein
J, Shafqat
S, Doherty
D, Chang
Y, Kurina
A, Furie
KL
Functional recovery after cerebellar stroke.
Stroke 2001; 32:530-4..
;
():
Gleason
SG, Furie
KL, Lev
M, O'Donnell
J, McMahon
PM, Beinfeld
MT, Halpern
E, Mullins
M, Harris
G, Koroshetz
WJ, Gazelle
GS
Potential Influence of Acute CT imaging on inpatient costs in ischemic stroke.
Academic Radiology 2001; 8:955-64..
;
():
Mohr
JP, Thompson
JL, Levin
B, Sacco
RL, Furie
KL, Kistler
JP, Albers
GW, Pettigrew
LC, Adams
HP Jr, Jackson
CM, Pullicino
P
A comparison of warfarin and aspirin for the prevention of recurrent ischemic stroke.
N Engl J Med 2001; 345:1444-51..
;
():
Kelly
PJ, Rosand
J, Plomaritoglou
A, Kistler
JP, Shih
VE, Silveira
S, Plomaritoglou
A, Furie
KL
Homocysteine, MTHFR 677CàT polymorphism, and risk of ischemic stroke: results of a meta-analysis.
Neurology 2002; 59: 529-36..
;
():
Ay
H, Oliveira-Filho
J, Buonanno
FS, Schafer
PW, Barron
M, Furie
KL, Chang
YC, Schwamm
LH, Gonzalez
RG, Koroshetz
WJ
Footprints of transient ischemic attacks: a diffusion-weighted MRI study.
Cerebrovascular Dis 2002; 14:177-86..
;
():
Kelly
PJ, Barron
M, Furie
KL
Hyperhomocysteinemia, MTHFR C677CàT polymorphism, and stroke.
Stroke 2002; 33: 1452-3..
;
():
Glantz
MJ, Cole
BF, Friedberg
MH, Lathi
E, Furie
KL, Akerley
W, Wahlberg
L, Lekos
A, Louis
S
A randomized, blinded, placebo-controlled trial of divalproex sodium prophylaxis in adults with newly diagnosed brain tumors.
Neurology 1996; 46: 985-91..
;
():
Suwanwela
N, Can
U, Furie
KL, Southern
JF, Mcdonald
NR, Ogilvy
CS, Hansen
CJ, Buonanno
FS, Abbott
WM, Koroshetz
WJ, Kistler
JP
Carotid Doppler ultrasound criteria for internal carotid artery stenosis based on residual lumen diameter calculated from en bloc carotid endarterectomy specimens.
Stroke 1996; 27: 1965-69..
;
():
Wilterdink
JL, Feldmann
E, Furie
KL, Bragoni
M, Benavides
J
"A transcranial Doppler ultrasound battery reliably identifies severe internal carotid artery stenosis,"
Stroke 1997, 28;133-6..
;
():
Can
U, Furie
KL, Suwanwela
N, Southern
JF, Macdonald
NR, Ogilvy
CS, Buonanno
FS, Koroshetz
WJ, Kistler
JP
Transcranial Doppler ultrasound criteria for internal carotid artery stenosis based on residual lumen diameter calculated from en bloc carotid endarterectomy specimens.
Stroke 1997; 28: 1966-71..
;
():
Furie
KL, Wilterdink
JL
The epidemiology of stroke: a focus on Rhode Island.
Medicine and Health Rhode Island 1997; 80: 142-5..
;
():
Furie
KL
The WARSS, APASS, HAS and Genesis Study Groups*. The feasibility of a collaborative double-blind study using an anticoagulant.
Cerebrovasc Dis 1997; 7:100-12..
;
():
Ay
H, Furie
KL, Koroshetz
W
Diffusion-weighted MRI characterizes the ischemic lesion in transient global amnesia.
Neurology 1998; 51: 901-03..
;
():
Wilterdink
JL, Furie
KL, Easton
JD
Cardiac evaluation of stroke patients.
Neurology 1998; 51 Suppl 3: 23-6..
;
():
O'Donnell
HC, Rosand
J, Knudsen
KA, Furie
KL, Segal
AZ, Chiu
RI, Ikeda
D, Greenberg
SM
Apolipoprotein E genotype and the risk of recurrent lobar intracerebral hemorrhage.
N Engl J Med 2000; 342: 240-45..
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():
Furie
KL
Antiphospholipid Antibodies in Stroke Study Group*. Anticardiolipin antibodies are an independent risk factor for first ischemic stroke.
Neurology 1993; 43: 2069-73..
;
():
Ickenstein
GW, Kelly
PJ, Furie
KL, Ambrosi
D, Rallis
N, Goldstein
R, Horick
N, Stein
J
Predictors of feeding gastrostomy tube removal in stroke patients with dysphagia.
J Stroke Cerebrovasc Dis.
;
12
(4):
169-174
Ay
H, Benner
T, Arsava
EM, Furie
KL, Singhal
AB, Jensen
MB, Ayata
C, Towfighi
A, Smith
EE, Chong
JY, Koroshetz
WJ, Sorensen
AG
A Computerized Algorithm for Etiologic Classification of Ischemic Stroke. The Causative Classification of Stroke System.
Stroke.
2007
Sep
27;
():
Furie
KL, Smith
EE
Metabolic syndrome: a target for preventing leukoaraiosis and age-related dementia?
Neurology.
2007
Sep
4;
69
(10):
951-2
Phillips
SJ, Dai
D, Mitnitski
A, Gubitz
GJ, Johnston
KC, Koroshetz
WJ, Furie
KL, Black
S, Heiselman
DE,
Clinical diagnosis of lacunar stroke in the first 6 hours after symptom onset: analysis of data from the glycine antagonist in neuroprotection (GAIN) Americas trial.
Stroke.
2007
Oct
;
38
(10):
2706-11
Glymour
MM, Berkman
LF, Ertel
KA, Fay
ME, Glass
TA, Furie
KL
Lesion characteristics, NIH stroke scale, and functional recovery after stroke.
Am J Phys Med Rehabil.
2007
Sep
;
86
(9):
725-33
Gudbjartsson
DF, Arnar
DO, Helgadottir
A, Gretarsdottir
S, Holm
H, Sigurdsson
A, Jonasdottir
A, Baker
A, Thorleifsson
G, Kristjansson
K, Palsson
A, Blondal
T, Sulem
P, Backman
VM, Hardarson
GA, Palsdottir
E, Helgason
A, Sigurjonsdottir
R, Sverrisson
JT, Kostulas
K, Ng
MC, Baum
L, So
WY, Wong
KS, Chan
JC, Furie
KL, Greenberg
SM, Sale
M, Kelly
P, MacRae
CA, Smith
EE, Rosand
J, Hillert
J, Ma
RC, Ellinor
PT, Thorgeirsson
G, Gulcher
JR, Kong
A, Thorsteinsdottir
U, Stefansson
K
Variants conferring risk of atrial fibrillation on chromosome 4q25.
Nature.
2007
Jul
19;
448
(7151):
353-7
Camargo
EC, Furie
KL, Singhal
AB, Roccatagliata
L, Cunnane
ME, Halpern
EF, Harris
GJ, Smith
WS, Gonzalez
RG, Koroshetz
WJ, Lev
MH
Acute brain infarct: detection and delineation with CT angiographic source images versus nonenhanced CT scans.
Radiology.
2007
Aug
;
244
(2):
541-8
Howard
VJ, Furie
KL, Wang
CH, Sides
EG, Toole
JF
The changing risk factor profile of participants enrolled in a secondary stroke prevention trial: Vitamin intervention for stroke prevention.
Neuroepidemiology.
2006
;
27
(4):
222-9
Furie
KL
Ask the doctor. For the last few years, I have been experiencing what I think are mini-strokes. The first time it happened, I lost the sight in one eye for about a minutes. Sometimes the vision in both eyes gets blurred for a few minutes. A few weeks ago I could not think of the word "battery" while talking with a friend. Otherwise, I am a healthy 77-year-old who exercises, isn't overweight, and doesn't smoke. My doctor hasn't suggested any tests of courses of action. Can you?
Harv Heart Lett.
2006
Jun
;
16
(10):
8
Takaya
N, Cai
J, Ferguson
MS, Yarnykh
VL, Chu
B, Saam
T, Polissar
NL, Sherwood
J, Cury
RC, Anders
RJ, Broschat
KO, Hinton
D, Furie
KL, Hatsukami
TS, Yuan
C
Intra- and interreader reproducibility of magnetic resonance imaging for quantifying the lipid-rich necrotic core is improved with gadolinium contrast enhancement.
J Magn Reson Imaging.
2006
Jul
;
24
(1):
203-10
Ning
M, Furie
KL, Koroshetz
WJ, Lee
H, Barron
M, Lederer
M, Wang
X, Zhu
M, Sorensen
AG, Lo
EH, Kelly
PJ
Association between tPA therapy and raised early matrix metalloproteinase-9 in acute stroke.
Neurology.
2006
May
23;
66
(10):
1550-5
Furie
KL, Kelly
PJ
Homocyst(e)ine and stroke.
Semin Neurol.
2006
Feb
;
26
(1):
24-32
Hinton
DP, Cury
RC, Chan
RC, Wald
LL, Sherwood
JB, Furie
KL, Pitts
JT, Schmitt
F
Bright and black blood imaging of the carotid bifurcation at 3.0T.
Eur J Radiol.
2006
Mar
;
57
(3):
403-11
Cury
RC, Houser
SL, Furie
KL, Stone
JR, Ogilvy
CS, Sherwood
JB, Muller
JE, Brady
TJ, Hinton
DP
Vulnerable plaque detection by 3.0 tesla magnetic resonance imaging.
Invest Radiol.
2006
Feb
;
41
(2):
112-5
Ay
H, Furie
KL, Singhal
A, Smith
WS, Sorensen
AG, Koroshetz
WJ
An evidence-based causative classification system for acute ischemic stroke.
Ann Neurol.
2005
Nov
;
58
(5):
688-97
Cronin
S, Furie
KL, Kelly
PJ
Dose-related association of MTHFR 677T allele with risk of ischemic stroke: evidence from a cumulative meta-analysis.
Stroke.
2005
Jul
;
36
(7):
1581-7
Ning
MM, Smirnakis
S, Furie
KL, Sheen
VL
Adult acute disseminated encephalomyelitis associated with poststreptococcal infection.
J Clin Neurosci.
2005
Apr
;
12
(3):
298-300
Wang
X, Tsuji
K, Lee
SR, Ning
M, Furie
KL, Buchan
AM, Lo
EH
Mechanisms of hemorrhagic transformation after tissue plasminogen activator reperfusion therapy for ischemic stroke.
Stroke.
2004
Nov
;
35
(11 Suppl 1):
2726-30
Furie
KL, Rosenberg
R, Thompson
JL, Bauer
K, Mohr
JP, Rosner
B, Sciacca
R, Barzegar
S, Thornell
B, Costigan
T, Kistler
JP
Thrombin generation in non-cardioembolic stroke subtypes: the Hemostatic System Activation Study.
Neurology.
2004
Sep
14;
63
(5):
777-84
Shafqat
S, Kelly
PJ, Furie
KL
Holter monitoring in the diagnosis of stroke mechanism.
Intern Med J.
2004
Jun
;
34
(6):
305-9