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Jonathan Rosand, M.D., M.Sc.

Jonathan Rosand, MD

Titles and Contact Information

Chief, Neurocritical Care and Emergency Neurology, Massachusetts General Hospital

Director, Massachusetts General HospitalNeuroscience Intensive Care Unit

Faculty Member, Massachusetts General Hospital, Center for Human Genetic Research

Associate Professor of Neurology, Harvard Medical School

Appointments: (617) 726-8459
Fax Number: (617) 724-5043

Affiliations and Profiles

  • Neurology Clinical Trials Unit
  • Neuroscience Intensive Care Unit

Clinical Interests

  • Recovery from acute brain injury
  • NeuroCritical Care
  • Hemorrhagic and ischemic stroke
  • Genetics

Clinical Background

1994 M.D. Degree Columbia University
College of Physicians & Surgeons
1996 Residency Massachusetts General Hospital
1999 Residency/Chief Residency Massachusetts General Hospital
2000 Board Certification Neurology
2001 Fellowship Massachusetts General Hospital
Stroke & NeuroCritical Care
2001 Harvard School of Public Health
2008 Board Certification Vascular Neurology
2008 Board Certification Neurocritical Care


Biffi A, Anderson CD, Jagiella JM, Schmidt H, Kissela B, Hansen BM, Jimenez-Conde J, Pires CR, Ayres AM, Schwab K, Cortellini L, Pera J, Urbanik A, Romero JM, Rost NS, Goldstein JN, Viswanathan A, Pichler A, Enzinger C, Rabionet R, Norrving B, Tirschwell DL, Selim M, Brown DL, Silliman SL, Worrall BB, Meschia JF, Kidwell CS, Broderick JP, Greenberg SM, Roquer J, Lindgren A, Slowik A, Schmidt R, Woo D, Rosand J, on behalf of the International Stroke Genetics Consortium
APOE genotype and extent of bleeding and outcome in lobar intracerebral haemorrhage: a genetic association study.
Lancet Neurol. 2011 Aug ; 10 (8): 702-709

Wijman CA, Smirnakis SM, Vespa P, Szigeti K, Ziai WC, Ning MM, Rosand J, Hanley DF, Geocadin R, Hall C, Le Roux PD, Suarez JI, Zaidat OO, For the First Neurocritical Care Research Conference Investigators
Research and Technology in Neurocritical Care.
Neurocrit Care. 2011 Jul 28; ():

Biffi A, Devan WJ, Anderson CD, Ayres AM, Schwab K, Cortellini L, Viswanathan A, Rost NS, Smith EE, Goldstein JN, Greenberg SM, Rosand J
Statin use and outcome after intracerebral hemorrhage: case-control study and meta-analysis.
Neurology. 2011 May 3; 76 (18): 1581-8

Anderson CD, Biffi A, Rahman R, Ross OA, Jagiella JM, Kissela B, Cole JW, Cortellini L, Rost NS, Cheng YC, Greenberg SM, de Bakker PI, Brown RD, Brott TG, Mitchell BD, Broderick JP, Worrall BB, Furie KL, Kittner SJ, Woo D, Slowik A, Meschia JF, Saxena R, Rosand J, on behalf of the International Stroke Genetics Consortium
Common mitochondrial sequence variants in ischemic stroke.
Ann Neurol. 2011 Mar ; 69 (3): 471-80

Anderson CD, Nalls MA, Biffi A, Rost NS, Greenberg SM, Singleton AB, Meschia JF, Rosand J
The effect of survival bias on case-control genetic association studies of highly lethal diseases.
Circ Cardiovasc Genet. 2011 Apr ; 4 (2): 188-96

Thompson BB, Béjot Y, Caso V, Castillo J, Christensen H, Flaherty ML, Foerch C, Ghandehari K, Giroud M, Greenberg SM, Hallevi H, Hemphill JC, Heuschmann P, Juvela S, Kimura K, Myint PK, Nagakane Y, Naritomi H, Passero S, Rodríguez-Yáñez MR, Roquer J, Rosand J, Rost NS, Saloheimo P, Salomaa V, Sivenius J, Sorimachi T, Togha M, Toyoda K, Turaj W, Vemmos KN, Wolfe CD, Woo D, Smith EE
Prior antiplatelet therapy and outcome following intracerebral hemorrhage: a systematic review.
Neurology. 2010 Oct 12; 75 (15): 1333-42

Arsava EM, Ballabio E, Benner T, Cole JW, Delgado-Martinez MP, Dichgans M, Fazekas F, Furie KL, Illoh K, Jood K, Kittner S, Lindgren AG, Majersik JJ, Macleod MJ, Meurer WJ, Montaner J, Olugbodi AA, Pasdar A, Redfors P, Schmidt R, Sharma P, Singhal AB, Sorensen AG, Sudlow C, Thijs V, Worrall BB, Rosand J, Ay H, on behalf of the International Stroke Genetics Consortium
The Causative Classification of Stroke system: an international reliability and optimization study.
Neurology. 2010 Oct 5; 75 (14): 1277-84

Biffi A, Anderson CD, Nalls MA, Rahman R, Sonni A, Cortellini L, Rost NS, Matarin M, Hernandez DG, Plourde A, de Bakker PI, Ross OA, Greenberg SM, Furie KL, Meschia JF, Singleton AB, Saxena R, Rosand J
Principal-component analysis for assessment of population stratification in mitochondrial medical genetics.
Am J Hum Genet. 2010 Jun 11; 86 (6): 904-17

Rost NS, Fitzpatrick K, Biffi A, Kanakis A, Devan W, Anderson CD, Cortellini L, Furie KL, Rosand J
White matter hyperintensity burden and susceptibility to cerebral ischemia.
Stroke. 2010 Dec ; 41 (12): 2807-11

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In the News

The MGH Neurology Department placed 4th in US News Neurology / NeuroSurgery rankings for 2013-14.

Educational Video

Still from the Stroke Evaluation simulation

This video simulation of an Emergency stroke evaluation illustrates the care of patients with acute stroke by the MGH Acute Stroke team.