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Ferdinando S. Buonanno, M.D.

Ferdinando S. Buonanno, M.D.

Title and Contact Information

Assistant Professor of Neurology, Harvard Medical School

Appointments: (617) 726-8459
Fax Number: (617) 726-5043

Affiliations and Profiles

Clinical Interests

  • Stroke and Other Cerebrovascular Disorders
  • Pediatric and Young Stroke
  • Neurocritical care
  • Cardioneurology
  • Patent Foramen Ovale (PFO) and Stroke

Clinical Background

1973 M.D. Degree University of Padova, Italy
1978 Residency Bowman Gray School of Medicine
1979 Fellowship Bowman Gray School of Medicine
1981 Fellowship Massachusetts General Hospital
Stroke and Cerebral Blood Flow
1981 Board Certification Neurology


Florez JC, Ay H, Van Cott EM, Buonanno FS
Patent foramen ovale and hypercoagulability as combined risk factors for stroke.
J Stroke Cerebrovasc Dis. ; 12 (3): 114-8

Nogueira RG, Bodock MJ, Koroshetz WJ, Topcuoglu MA, Carter BS, Ogilvy CS, Pryor JC, Buonanno FS
High-dose Bosentan in the Prevention and Treatment of Subarachnoid Hemorrhage-induced Cerebral Vasospasm: An Open-label Feasibility Study.
Neurocrit Care. 2007 Sep 28; ():

Grabowski EF, Buonanno FS, Krishnamoorthy K
Prothrombotic risk factors in the evaluation and management of perinatal stroke.
Semin Perinatol. 2007 Aug ; 31 (4): 243-9

Schwamm LH, Rosenthal ES, Swap CJ, Rosand J, Rordorf G, Buonanno FS, Vangel MG, Koroshetz WJ, Lev MH
Hypoattenuation on CT angiographic source images predicts risk of intracerebral hemorrhage and outcome after intra-arterial reperfusion therapy.
AJNR Am J Neuroradiol. 2005 Aug ; 26 (7): 1798-803

Badjatia N, Topcuoglu MA, Buonanno FS, Smith EE, Nogueira RG, Rordorf GA, Carter BS, Ogilvy CS, Singhal AB
Relationship between hyperglycemia and symptomatic vasospasm after subarachnoid hemorrhage.
Crit Care Med. 2005 Jul ; 33 (7): 1603-9; quiz 1623

Singhal AB, Benner T, Roccatagliata L, Koroshetz WJ, Schaefer PW, Lo EH, Buonanno FS, Gonzalez RG, Sorensen AG
A pilot study of normobaric oxygen therapy in acute ischemic stroke.
Stroke. 2005 Apr ; 36 (4): 797-802

Topçuoglu MA, Palacios IF, Buonanno FS
Contrast M-mode power Doppler ultrasound in the detection of right-to-left shunts: utility of submandibular internal carotid artery recording.
J Neuroimaging. 2003 Oct ; 13 (4): 315-23

Topçuoglu MA, Buonanno FS
Importance of jugular valve incompetence in contrast transcranial Doppler ultrasonography for the diagnosis of patent foramen ovale.
J Neuroimaging. 2003 Jul ; 13 (3): 272-5

Topcuoglu MA, Ogilvy CS, Carter BS, Buonanno FS, Koroshetz WJ, Singhal AB
Subarachnoid hemorrhage without evident cause on initial angiography studies: diagnostic yield of subsequent angiography and other neuroimaging tests.
J Neurosurg. 2003 Jun ; 98 (6): 1235-40

Hunter GJ, Silvennoinen HM, Hamberg LM, Koroshetz WJ, Buonanno FS, Schwamm LH, Rordorf GA, Gonzalez RG
Whole-brain CT perfusion measurement of perfused cerebral blood volume in acute ischemic stroke: probability curve for regional infarction.
Radiology. 2003 Jun ; 227 (3): 725-30

Portera-Cailliau C, Doherty CP, Buonanno FS, Feske SK
Middle cerebral artery territory infarction sparing the precentral gyrus: report of three cases.
J Neurol Neurosurg Psychiatry. 2003 Apr ; 74 (4): 510-2

Singhal AB, Newstein MC, Budzik R, Cha JH, Rordorf G, Buonanno FS, Panzara MA
Diffusion-weighted magnetic resonance imaging abnormalities in Bartonella encephalopathy.
J Neuroimaging. 2003 Jan ; 13 (1): 79-82

Ay H, Oliveira-Filho J, Buonanno FS, Schaefer PW, Furie KL, Chang YC, Rordorf G, Schwamm LH, Gonzalez RG, Koroshetz WJ
'Footprints' of transient ischemic attacks: a diffusion-weighted MRI study.
Cerebrovasc Dis. 2002 ; 14 (3-4): 177-86

Singhal AB, Topcuoglu MA, Buonanno FS
Acute ischemic stroke patterns in infective and nonbacterial thrombotic endocarditis: a diffusion-weighted magnetic resonance imaging study.
Stroke. 2002 May ; 33 (5): 1267-73

Nestoridi E, Buonanno FS, Jones RM, Krishnamoorthy K, Grant PE, Van Cott EM, Grabowski EF
Arterial ischemic stroke in childhood: the role of plasma-phase risk factors.
Curr Opin Neurol. 2002 Apr ; 15 (2): 139-44

Greer DM, Buonanno FS
Cerebral infarction in conjunction with patent foramen ovale and May-Thurner syndrome.
J Neuroimaging. 2001 Oct ; 11 (4): 432-4

Lev MH, Segal AZ, Farkas J, Hossain ST, Putman C, Hunter GJ, Budzik R, Harris GJ, Buonanno FS, Ezzeddine MA, Chang Y, Koroshetz WJ, Gonzalez RG, Schwamm LH
Utility of perfusion-weighted CT imaging in acute middle cerebral artery stroke treated with intra-arterial thrombolysis: prediction of final infarct volume and clinical outcome.
Stroke. 2001 Sep ; 32 (9): 2021-8

Buonanno FS
Cerebral Sinovenous Thrombosis.
Curr Treat Options Cardiovasc Med. 2001 Oct ; 3 (5): 417-427

Lev MH, Farkas J, Rodriguez VR, Schwamm LH, Hunter GJ, Putman CM, Rordorf GA, Buonanno FS, Budzik R, Koroshetz WJ, Gonzalez RG
CT angiography in the rapid triage of patients with hyperacute stroke to intraarterial thrombolysis: accuracy in the detection of large vessel thrombus.
J Comput Assist Tomogr. ; 25 (4): 520-8

Oliveira-Filho J, Ezzeddine MA, Segal AZ, Buonanno FS, Chang Y, Ogilvy CS, Rordorf G, Schwamm LH, Koroshetz WJ, McDonald CT
Fever in subarachnoid hemorrhage: relationship to vasospasm and outcome.
Neurology. 2001 May 22; 56 (10): 1299-304

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In the News

The MGH Neurology Department placed 4th in US News Neurology / NeuroSurgery rankings for 2013-14.

Educational Video

Still from the Stroke Evaluation simulation

This video simulation of an Emergency stroke evaluation illustrates the care of patients with acute stroke by the MGH Acute Stroke team.